Remodeling and Vascular Spaces in Bone
نویسندگان
چکیده
منابع مشابه
Metalloproteinases, Mechanical Factors and Vascular Remodeling
Chronic increases in arterial blood flow elicit an adaptive response of the arterial wall, leading to vessel enlargement and reduction in wall shear stress to physiological baseline value. Release of nitric oxide from endothelial cells exposed to excessive shear is a fundamental step in the remodeling process, and potentially triggers a cascade of events, including growth factor induction and m...
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1Department of Medicine and Bioregulatory Sciences, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan 2Department of Molecular Cardiovascular Biology and Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa, Ehime Tōon 791-0295, Japan 3Department of Cardiology, Nagoya University Graduate School of Medi...
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Background—Both matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) have been postulated to play roles in the pathophysiology of giant cell arteritis (GCA) because of their ability to degrade elastin. Understanding the specific mediators of arterial damage in GCA could lead to new therapeutic targets in this disease. Methods and Results—Temporal artery biopsy specimens were obtained from 147 cons...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2006
ISSN: 0884-0431
DOI: 10.1359/jbmr.060910